Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.
DNA methylation patterns are reprogrammed in primordial germ cells and in preimplantation embryos by demethylation and subsequent de novo methylation. It has been suggested that epigenetic reprogramming may be necessary for the embryonic genome to return to a pluripotent state. We have carried out a...
Main Authors: | Cassandra R Farthing, Gabriella Ficz, Ray Kit Ng, Chun-Fung Chan, Simon Andrews, Wendy Dean, Myriam Hemberger, Wolf Reik |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-06-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2432031?pdf=render |
Similar Items
-
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism
by: Oliver Hahn, et al.
Published: (2017-03-01) -
Epigenetic Reprogramming Induced Pluripotency
by: Anna Meiliana, et al.
Published: (2011-08-01) -
Reprogramming and epigenetic factors regulating pluripotency and the stem cell state
by: Wang, Stan
Published: (2015) -
Induced pluripotent stem cells reprogramming: Epigenetics and applications in the regenerative medicine
by: Kátia Maria Sampaio Gomes, et al. -
Epigenetic reprogramming of epiblast stem cells to a naïve pluripotent state
by: Gillich, Astrid
Published: (2012)