The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.

The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.

Survivin is a component of the chromosomal passenger complex (CPC) that is essential for accurate chromosome segregation. Interfering with the function of Survivin in mitosis leads to chromosome segregation errors and defective cytokinesis. Survivin contains a Baculovirus IAP Repeat (BIR) and theref...

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Bibliographic Details
Main Authors: Masato Hori, Tomoharu Miki, Mayumi Okamoto, Futoshi Yazama, Hiroaki Konishi, Hiroshi Kaneko, Fumio Shimamoto, Takahide Ota, Achim Temme, Masaaki Tatsuka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3565976?pdf=render

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http://europepmc.org/articles/PMC3565976?pdf=render

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