Optimizing Active Tumor Targeting Biocompatible Polymers for Efficient Systemic Delivery of Adenovirus

Adenovirus (Ad) has risen to be a promising alternative to conventional cancer therapy. However, systemic delivery of Ad, which is necessary for the treatment of metastatic cancer, remains a major challenge within the field, owing to poor tumor tropism and nonspecific hepatic tropism of the virus. T...

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Bibliographic Details
Main Authors: Jun Young Lee, Jin Woo Hong, Thavasyappan Thambi, A-Rum Yoon, Joung-Woo Choi, Yi Li, Quang Nam Bui, Doo Sung Lee, Chae-Ok Yun
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/8/1896