Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid.

Emergence of a globally dominant IncHI1 plasmid type associated with multiple drug resistant typhoid.

Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), remains a serious global health concern. Since their emergence in the mid-1970s multi-drug resistant (MDR) S. Typhi now dominate drug sensitive equivalents in many regions. MDR in S. Typhi is almost exclusively conferred by self-...

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Bibliographic Details
Main Authors: Kathryn E Holt, Minh Duy Phan, Stephen Baker, Pham Thanh Duy, Tran Vu Thieu Nga, Satheesh Nair, A Keith Turner, Ciara Walsh, Séamus Fanning, Sinéad Farrell-Ward, Shanta Dutta, Sam Kariuki, François-Xavier Weill, Julian Parkhill, Gordon Dougan, John Wain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3139670?pdf=render

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http://europepmc.org/articles/PMC3139670?pdf=render

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