CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals

CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals

Cerebrospinal fluid (CSF) YKL40 and sTREM2 are astroglial and microglial activity biomarkers, respectively. We assessed whether CSF YKL40 and sTREM2 baseline levels are associated with longitudinal brain volume and diffusivity changes in cognitively unimpaired adults. Two brain MRI scans of 36 parti...

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Bibliographic Details
Main Authors: Carles Falcon, Gemma C. Monté-Rubio, Oriol Grau-Rivera, Marc Suárez-Calvet, Raquel Sánchez-Valle, Lorena Rami, Beatriz Bosch, Christian Haass, Juan Domingo Gispert, José Luis Molinuevo
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158219301512

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http://www.sciencedirect.com/science/article/pii/S2213158219301512

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