Unsaponifiable and phenolic fractions from virgin olive oil prevent neuroinflammation skewing microglia polarization toward M2 phenotype

Inhibiting M1 microglia phenotype while stimulating M2 microglia phenotype has been suggested as potential therapeutic approach for the treatment of neuroinflammation-related diseases. Our aim was to evaluate the anti-neuroinflammatory effects of minor compounds found in unsaponifiable fraction (UF)...

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Bibliographic Details
Main Authors: Rocio Toscano, Maria C. Millan-Linares, Maria C. Naranjo, Ana Lemus-Conejo, Carmen Claro, Sergio Montserrat-de la Paz
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619304670