HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity

HSF1: Primary Factor in Molecular Chaperone Expression and a Major Contributor to Cancer Morbidity

Heat shock factor 1 (HSF1) is the primary component for initiation of the powerful heat shock response (HSR) in eukaryotes. The HSR is an evolutionarily conserved mechanism for responding to proteotoxic stress and involves the rapid expression of heat shock protein (HSP) molecular chaperones that pr...

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Bibliographic Details
Main Authors: Thomas L. Prince, Benjamin J. Lang, Martin E. Guerrero-Gimenez, Juan Manuel Fernandez-Muñoz, Andrew Ackerman, Stuart K. Calderwood
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
heat shock factor 1
HSF1
cancer
heat shock proteins
HSPs
molecular chaperones
Online Access:https://www.mdpi.com/2073-4409/9/4/1046

Internet

https://www.mdpi.com/2073-4409/9/4/1046

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