Overexpression of ABCC1 Confers Drug Resistance to Betulin

Betulin is a lupane-type pentacyclic triterpene, which is isolated from birch bark. It has a broad spectrum of biological and pharmacological properties, such as anti-inflammatory, anti-tumor, anti-viral, and anti-bacterial activity. Herein, we explored the factors that may result in betulin resista...

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Bibliographic Details
Main Authors: Xuan-Yu Chen, Yuqi Yang, Jing-Quan Wang, Zhuo-Xun Wu, Jing Li, Zhe-Sheng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.640656/full