Regulation of Schistosoma mansoni development and reproduction by the mitogen-activated protein kinase signaling pathway.

BACKGROUND:Protein kinases are proven targets for drug development with an increasing number of eukaryotic Protein Kinase (ePK) inhibitors now approved as drugs. Mitogen-activated protein kinase (MAPK) family members connect cell-surface receptors to regulatory targets within cells and influence a n...

Full description

Bibliographic Details
Main Authors: Luiza Freire de Andrade, Marina de Moraes Mourão, Juliana Assis Geraldo, Fernanda Sales Coelho, Larissa Lopes Silva, Renata Heisler Neves, Angela Volpini, José Roberto Machado-Silva, Neusa Araujo, Rafael Nacif-Pimenta, Conor R Caffrey, Guilherme Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4063740?pdf=render