The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

Abstract Insights into tau molecular structures have advanced significantly in recent years. This field has been the subject of recent breakthroughs, including the first cryo-electron microscopy structures of tau filaments from Alzheimer’s and Pick’s disease inclusions, as well as the structure of t...

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Bibliographic Details
Main Authors: Yann Fichou, Youssra K. Al-Hilaly, François Devred, Caroline Smet-Nocca, Philipp O. Tsvetkov, Joke Verelst, Joris Winderickx, Nick Geukens, Eugeen Vanmechelen, Audrey Perrotin, Louise Serpell, Bernard J Hanseeuw, Miguel Medina, Luc Buée, Isabelle Landrieu
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Acta Neuropathologica Communications
Subjects:
Tauopathies
Alzheimer’s disease; tau structure; tau aggregation
Alzheimer’s disease diagnosis
Amyloid
Online Access:http://link.springer.com/article/10.1186/s40478-019-0682-x

Internet

http://link.springer.com/article/10.1186/s40478-019-0682-x

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