Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance

Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance

Fungal pathogens pose a serious threat to public health. Candida auris is an emerging fungal pathogen that is often resistant to commonly used antifungal drugs. However, the mechanisms governing drug resistance and virulence in this organism remain largely unexplored. In this study, we adapted a con...

Full description

Bibliographic Details
Main Authors: Sang Hu Kim, Kali R. Iyer, Lakhansing Pardeshi, José F. Muñoz, Nicole Robbins, Christina A. Cuomo, Koon Ho Wong, Leah E. Cowen
Format: Article
Language:English
Published: American Society for Microbiology 2019-01-01
Series:mBio
Subjects:
antifungal drug resistance
Candida albicans
Candida auris
Cdr1
developmental program
emerging pathogen
fungal morphogenesis
fungal pathogen
Hsp90
transcriptional program
Online Access:https://doi.org/10.1128/mBio.02529-18

Internet

https://doi.org/10.1128/mBio.02529-18

Similar Items