Genotype and Tumor Locus Determine Expression Profile of Pseudohypoxic Pheochromocytomas and Paragangliomas

Genotype and Tumor Locus Determine Expression Profile of Pseudohypoxic Pheochromocytomas and Paragangliomas

Pheochromocytomas (PHEOs) and paragangliomas (PGLs) related to mutations in the mitochondrial succinate dehydrogenase (SDH) subunits A, B, C, and D, SDH complex assembly factor 2, and the von Hippel-Lindau (VHL) genes share a pseudohypoxic expression profile. However, genotype-specific differences...

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Bibliographic Details
Main Authors: Uma Shankavaram, Stephanie M.J. Fliedner, Abdel G. Elkahloun, Jenifer J. Barb, Peter J. Munson, Thanh T. Huynh, Joey C. Matro, Hana Turkova, W. Marston Linehan, Henri J. Timmers, Arthur S. Tischler, James F. Powers, Ronald de Krijger, Bora E. Baysal, Martina Takacova, Silvia Pastorekova, David Gius, Hendrik Lehnert, Kevin Camphausen, Karel Pacak
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800504

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http://www.sciencedirect.com/science/article/pii/S1476558613800504

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