Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

Background & Aims: The fatty acid translocase, also known as CD36, is a well-established scavenger receptor for fatty acid (FA) uptake and is abundantly expressed in many metabolically active tissues. In the liver, CD36 is known to contribute to the progression of non-alcoholic fatty liver disea...

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Bibliographic Details
Main Authors: Paul F. Lebeau, Jae Hyun Byun, Khrystyna Platko, Ali A. Al-Hashimi, Šárka Lhoták, Melissa E. MacDonald, Aurora Mejia-Benitez, Annik Prat, Suleiman A. Igdoura, Bernardo Trigatti, Kenneth N. Maclean, Nabil G. Seidah, Richard C. Austin
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:JHEP Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555919301314

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http://www.sciencedirect.com/science/article/pii/S2589555919301314

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