The Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients

The Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients

Abstract HLA-B*27 is strongly associated with an inflammatory autoimmune disorder, the Ankylosing Spondylitis (AS) and plays a protective role in viral infections. The two aspects might be linked. In this work, we compared in B*2705/B*07 positive patients with AS, the CD8+ T cell responses to two im...

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Bibliographic Details
Main Authors: Valentina Tedeschi, Carolina Vitulano, Alberto Cauli, Fabiana Paladini, Matteo Piga, Alessandro Mathieu, Rosa Sorrentino, Maria Teresa Fiorillo
Format: Article
Language:English
Published: BMC 2016-05-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2016.00031

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http://link.springer.com/article/10.2119/molmed.2016.00031

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