DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system

DL4-μbeads induce T cell lineage differentiation from stem cells in a stromal cell-free system

T cells derived from stem cells can be harnessed for regenerative medicine and cancer immunotherapy, but current technologies limit production and translation. Here, the authors present a serum-free, stromal-cell free DLL4-coated microbead method for the scalable production of T-lineage cells from m...

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Bibliographic Details
Main Authors: Ashton C. Trotman-Grant, Mahmood Mohtashami, Joshua De Sousa Casal, Elisa C. Martinez, Dylan Lee, Sintia Teichman, Patrick M. Brauer, Jianxun Han, Michele K. Anderson, Juan Carlos Zúñiga-Pflücker
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25245-8

Internet

https://doi.org/10.1038/s41467-021-25245-8

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