Prodegenerative IκBα expression in oligodendroglial α-synuclein models of multiple system atrophy

Prodegenerative IκBα expression in oligodendroglial α-synuclein models of multiple system atrophy

Multiple system atrophy is a progressive, neurodegenerative disease characterized by parkinsonism, ataxia, autonomic dysfunction, and accumulation of α-synuclein in oligodendrocytes. To understand how α-synuclein aggregates impact oligodendroglial homeostasis, we investigated an oligodendroglial cel...

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Bibliographic Details
Main Authors: Christine L. Kragh, Amanda M. Gysbers, Edward Rockenstein, Karen Murphy, Glenda M. Halliday, Eliezer Masliah, Poul Henning Jensen
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Neurobiology of Disease
Subjects:
Multiple system atrophy
NF-κB
IκBα
α-Synuclein
Oligodendrocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113003380

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http://www.sciencedirect.com/science/article/pii/S0969996113003380

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