Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN

Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN

Objective: We tested the hypothesis that exercise training would attenuate metabolic impairment in a model of severe cancer cachexia. Methods: We used multiple in vivo and in vitro methods to explore the mechanisms underlying the beneficial effects induced by exercise training in tumor-bearing rats....

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Bibliographic Details
Main Authors: Christiano R.R. Alves, Willian das Neves, Ney R. de Almeida, Eric J. Eichelberger, Paulo R. Jannig, Vanessa A. Voltarelli, Gabriel C. Tobias, Luiz R.G. Bechara, Daniele de Paula Faria, Maria J.N. Alves, Lars Hagen, Animesh Sharma, Geir Slupphaug, José B.N. Moreira, Ulrik Wisloff, Michael F. Hirshman, Carlos E. Negrão, Gilberto de Castro Jr, Roger Chammas, Kathryn J. Swoboda, Jorge L. Ruas, Laurie J. Goodyear, Patricia C. Brum
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Metabolism
Subjects:
Cancer cachexia
Muscle wasting
Atrophy
Endurance exercise
Response elements
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820300867

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http://www.sciencedirect.com/science/article/pii/S2212877820300867

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