AKT1 and SELP polymorphisms predict the risk of developing cachexia in pancreatic cancer patients.

Pancreatic ductal adenocarcinoma (PDAC) patients have the highest risk of developing cachexia, which is a direct cause of reduced quality of life and shorter survival. Novel biomarkers to identify patients at risk of cachexia are needed and might have a substantial impact on clinical management. Her...

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Main Authors: Abolfazl Avan, Amir Avan, Tessa Y S Le Large, Andrea Mambrini, Niccola Funel, Mina Maftouh, Majid Ghayour-Mobarhan, Maurizio Cantore, Ugo Boggi, Godefridus J Peters, Paola Pacetti, Elisa Giovannetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0108057