Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid

Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid

The non-β-oxidisable tetradecylthioacetic acid (TTA) is incorporated into cellular membranes when C3H/10T1/2 cells are cultured in TTA-containing medium. We here demonstrate that this alteration in cellular membranes affect the nuclear translocation of proteins involved in signal transduction. Analy...

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Bibliographic Details
Main Authors: Bodil Bjørndal, Charlotte Helleland, Stig-Ove Bøe, Oddrun A. Gudbrandsen, Karl-Henning Kalland, Pavol Bohov, Rolf K. Berge, Johan R. Lillehaug
Format: Article
Language:English
Published: Elsevier 2002-10-01
Series:Journal of Lipid Research
Subjects:
TTA
mitogen-activated protein/extracellular signal-regulated kinase
protein kinase C
nuclear translocation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327826

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http://www.sciencedirect.com/science/article/pii/S0022227520327826

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