Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence

Background: Pharmacologic adherence measures were critical to the interpretation of the tenofovir (TFV)-disoproxil-fumarate/emtricitabine (TDF/FTC) PrEP trials. These measures are being incorporated into PrEP demonstration projects, but currently-available metrics in plasma, cells, hair or urine inv...

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Bibliographic Details
Main Authors: Monica Gandhi, Peter Bacchetti, Warren C. Rodrigues, Matthew Spinelli, Catherine A. Koss, Paul K. Drain, Jared M. Baeten, Nelly R. Mugo, Kenneth Ngure, Leslie Z. Benet, Hideaki Okochi, Guohong Wang, Michael Vincent
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537018300245