In vitro and in vivo experimental models for drug screening and development for Chagas disease

In vitro and in vivo experimental models for drug screening and development for Chagas disease

Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas of Latin America. Although the occurrence of acute cases sharply has declined due to Southern Cone Initiative efforts to control vector transmission, there still remain serious challenges, including the mainten...

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Bibliographic Details
Main Authors: Alvaro José Romanha, Solange Lisboa de Castro, Maria de Nazaré Correia Soeiro, Joseli Lannes-Vieira, Isabela Ribeiro, André Talvani, Bernadette Bourdin, Bethania Blum, Bianca Olivieri, Carlos Zani, Carmenza Spadafora, Egler Chiari, Eric Chatelain, Gabriela Chaves, José Eduardo Calzada, Juan Manuel Bustamante, Lucio H Freitas-Junior, Luz I Romero, Maria Terezinha Bahia, Michel Lotrowska, Milena Soares, Sonia Gumes Andrade, Tanya Armstrong, Wim Degrave, Zilton de Araújo Andrade
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2010-03-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Trypanosoma cruzi
Chagas disease treatment
drug screening
benznidazole
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000200022

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000200022

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