Chagas disease research and development: Is there light at the end of the tunnel?

by Eric Chatelain
Published 2017-01-01

Drug discovery and development for neglected diseases: the DNDi model

by Eric Chatelain, Jean-Robert Ioset
Published 2011-03-01

Drug Discovery for Chagas Disease: Impact of Different Host Cell Lines on Assay Performance and Hit Compound Selection

by Caio Haddad Franco, Laura Maria Alcântara, Eric Chatelain, Lucio Freitas-Junior, Carolina Borsoi Moraes
Published 2019-05-01

A Multi-Species Phenotypic Screening Assay for Leishmaniasis Drug Discovery Shows That Active Compounds Display a High Degree of Species-Specificity

by Laura M. Alcântara, Thalita C. S. Ferreira, Vanessa Fontana, Eric Chatelain, Carolina B. Moraes, Lucio H. Freitas-Junior
Published 2020-05-01

Clinical Practice Guidelines for Chagas Disease: Recent Developments and Future Needs

by Colin Forsyth, Andrea Marchiol, Rafael Herazo, Eric Chatelain, Carolina Batista, Nathalie Strub-Wourgaft, Graeme Bilbe, Sergio Sosa-Estani
Published 2019-03-01

Correction: Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

by Melissa L. Sykes, Jonathan B. Baell, Marcel Kaiser, Eric Chatelain, Sarah R. Moawad, Danny Ganame, Jean-Robert Ioset, Vicky M. Avery
Published 2013-01-01

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign.

by Melissa L Sykes, Jonathan B Baell, Marcel Kaiser, Eric Chatelain, Sarah R Moawad, Danny Ganame, Jean-Robert Ioset, Vicky M Avery
Published 2012-01-01

Correction: Identification of Compounds with Anti-Proliferative Activity against Strain 427 by a Whole Cell Viability Based HTS Campaign.

by Melissa L. Sykes, Jonathan B. Baell, Marcel Kaiser, Eric Chatelain, Sarah R. Moawad, Danny Ganame, Jean-Robert Ioset, Vicky M. Avery
Published 2013-01-01

An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages.

by Jair L Siqueira-Neto, Seunghyun Moon, Jiyeon Jang, Gyongseon Yang, Changbok Lee, Hong Kee Moon, Eric Chatelain, Auguste Genovesio, Jonathan Cechetto, Lucio H Freitas-Junior
Published 2012-01-01

Identification of Resistance Determinants for a Promising Antileishmanial Oxaborole Series

by Magali Van den Kerkhof, Philippe Leprohon, Dorien Mabille, Sarah Hendrickx, Lindsay B. Tulloch, Richard J. Wall, Susan Wyllie, Eric Chatelain, Charles E. Mowbray, Stéphanie Braillard, Marc Ouellette, Louis Maes, Guy Caljon
Published 2021-06-01

Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds.

by Jair L Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh, Jeong-Hun Sohn, Gyongseon Yang, Jiyoun Nam, Jiyeon Jang, Jonathan Cechetto, Chang Bok Lee, Seunghyun Moon, Auguste Genovesio, Eric Chatelain, Thierry Christophe, Lucio H Freitas-Junior
Published 2010-01-01

Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity

by Caio H. Franco, David C. Warhurst, Tapan Bhattacharyya, Ho Y.A. Au, Hai Le, Miriam A. Giardini, Bruno S. Pascoalino, Ana Claudia Torrecilhas, Lavinia M.D. Romera, Rafael Pedro Madeira, Sergio Schenkman, Lucio H. Freitas-Junior, Eric Chatelain, Michael A. Miles, Carolina B. Moraes
Published 2020-08-01

Target product profile for a test for the early assessment of treatment efficacy in Chagas disease patients: An expert consensus.

by Julio Alonso-Padilla, Marcelo Abril, Belkisyolé Alarcón de Noya, Igor C Almeida, Andrea Angheben, Tania Araujo Jorge, Eric Chatelain, Monica Esteva, Joaquim Gascón, Mario J Grijalva, Felipe Guhl, Alejandro Marcel Hasslocher-Moreno, Manuel Carlos López, Alejandro Luquetti, Oscar Noya, María Jesús Pinazo, Janine M Ramsey, Isabela Ribeiro, Andres Mariano Ruiz, Alejandro G Schijman, Sergio Sosa-Estani, M Carmen Thomas, Faustino Torrico, Maan Zrein, Albert Picado
Published 2020-04-01

In vitro and in vivo experimental models for drug screening and development for Chagas disease

by Alvaro José Romanha, Solange Lisboa de Castro, Maria de Nazaré Correia Soeiro, Joseli Lannes-Vieira, Isabela Ribeiro, André Talvani, Bernadette Bourdin, Bethania Blum, Bianca Olivieri, Carlos Zani, Carmenza Spadafora, Egler Chiari, Eric Chatelain, Gabriela Chaves, José Eduardo Calzada, Juan Manuel Bustamante, Lucio H Freitas-Junior, Luz I Romero, Maria Terezinha Bahia, Michel Lotrowska, Milena Soares, Sonia Gumes Andrade, Tanya Armstrong, Wim Degrave, Zilton de Araújo Andrade
Published 2010-03-01