Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea.

Clostridium difficile infections are an emerging health problem in the modern hospital environment. Severe alterations of the gut microbiome with loss of resistance to colonization against C. difficile are thought to be the major trigger, but there is no clear concept of how C. difficile infection e...

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Bibliographic Details
Main Authors: Henrik Knecht, Sven C Neulinger, Femke Anouska Heinsen, Carolin Knecht, Anke Schilhabel, Ruth A Schmitz, Alexandra Zimmermann, Vitor Martins dos Santos, Manuel Ferrer, Philip C Rosenstiel, Stefan Schreiber, Anette K Friedrichs, Stephan J Ott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938479?pdf=render