Clinical Development of Immune Checkpoint Inhibitors

Recent progress in cancer immunotherapy has been remarkable. Most striking are the clinical development and approval of immunomodulators, also known as immune checkpoint inhibitors. These monoclonal antibodies (mAb) are directed to immune checkpoint molecules, which are expressed on immune cells and...

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Bibliographic Details
Main Authors: Ayumu Ito, Shunsuke Kondo, Kohei Tada, Shigehisa Kitano
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/605478