Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

Objective: The metabolic master-switch AMP-activated protein kinase (AMPK) mediates insulin-independent glucose uptake in muscle and regulates the metabolic activity of brown and beige adipose tissue (BAT). The regulatory AMPKγ3 isoform is uniquely expressed in skeletal muscle and potentially in BAT...

Full description

Bibliographic Details
Main Authors: Philipp Rhein, Eric M. Desjardins, Ping Rong, Danial Ahwazi, Nicolas Bonhoure, Jens Stolte, Matthieu D. Santos, Ashley J. Ovens, Amy M. Ehrlich, José L. Sanchez Garcia, Qian Ouyang, Julian M. Yabut, Mads Kjolby, Mathieu Membrez, Niels Jessen, Jonathan S. Oakhill, Jonas T. Treebak, Pascal Maire, John W. Scott, Matthew J. Sanders, Patrick Descombes, Shuai Chen, Gregory R. Steinberg, Kei Sakamoto
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Metabolism
Subjects:
AMP-activated protein kinase
5-aminoimidazole-4-carboxamide riboside
MK-8722
TBC1D1
Brown adipose tissue
Beige adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000739

Internet

http://www.sciencedirect.com/science/article/pii/S2212877821000739

Similar Items