Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

Although respiratory syncytial virus (RSV) is responsible for more human deaths each year than influenza, its pathogenic mechanisms are poorly understood. Here high-resolution quantitative imaging, bioenergetics measurements and mitochondrial membrane potential- and redox-sensitive dyes are used to...

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Bibliographic Details
Main Authors: MengJie Hu, Keith E Schulze, Reena Ghildyal, Darren C Henstridge, Jacek L Kolanowski, Elizabeth J New, Yuning Hong, Alan C Hsu, Philip M Hansbro, Peter AB Wark, Marie A Bogoyevitch, David A Jans
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
respiratory syncytial virus
infection
mitochondria
reactive oxygen species
Online Access:https://elifesciences.org/articles/42448

Internet

https://elifesciences.org/articles/42448

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