Putative Autoantigen Leiomodin-1 Is Expressed in the Human Brain and in the Membrane Fraction of Newly Formed Neurons

Putative Autoantigen Leiomodin-1 Is Expressed in the Human Brain and in the Membrane Fraction of Newly Formed Neurons

Nodding syndrome is a pediatric epilepsy disorder associated with <i>Onchocerca volvulus</i> infection, but the mechanism driving this relationship is unclear. One hypothesis proposes that parasite-induced immune responses cross-react with human leiomodin-1 resulting in immune-mediated c...

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Bibliographic Details
Main Authors: David W. Nauen, Michael C. Haffner, Juyun Kim, Qizhi Zheng, Hao Yin, Angelo M. DeMarzo, Vasiliki Machairaki, Carlo Colantuoni, J. Geoffrey Pickering, Tory P. Johnson
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Pathogens
Subjects:
nodding syndrome
leiomodin-1
autoantibody
CNS
neuron
membrane
Online Access:https://www.mdpi.com/2076-0817/9/12/1036

Internet

https://www.mdpi.com/2076-0817/9/12/1036

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