Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition.

Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition.

We tested the hypothesis that Crohn's disease (CD)-related genetic polymorphisms involved in host innate immunity are associated with shifts in human ileum-associated microbial composition in a cross-sectional analysis of human ileal samples. Sanger sequencing of the bacterial 16S ribosomal RNA...

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Bibliographic Details
Main Authors: Ellen Li, Christina M Hamm, Ajay S Gulati, R Balfour Sartor, Hongyan Chen, Xiao Wu, Tianyi Zhang, F James Rohlf, Wei Zhu, Chi Gu, Charles E Robertson, Norman R Pace, Edgar C Boedeker, Noam Harpaz, Jeffrey Yuan, George M Weinstock, Erica Sodergren, Daniel N Frank
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3374607?pdf=render

Internet

http://europepmc.org/articles/PMC3374607?pdf=render

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