Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesicles.

Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesicles.

Tumours defined as Ewing sarcoma (ES) constitute a group of highly malignant neoplasms that most often affect children and young adults in the first 2 decades of life. The EWS/Fli-1 fusion gene, a product of the translocation t(11;22) (q24; 12), is detected in 95% of ES patients. Recently, it was va...

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Bibliographic Details
Main Authors: Masanori Tsugita, Nami Yamada, Shunsuke Noguchi, Kazunari Yamada, Hiroshi Moritake, Katsuji Shimizu, Yukihiro Akao, Takatoshi Ohno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790721?pdf=render

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http://europepmc.org/articles/PMC3790721?pdf=render

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