Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

Toxicological responses to chemical insult are largely regulated by transcriptionally activated pathways that may be independent, correlated and partially or fully overlapping. Investigating the dynamics of the interactions between stress responsive transcription factors from toxicogenomic data and...

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Bibliographic Details
Main Authors: Elias Zgheib, Alice Limonciel, Xiaoqi Jiang, Anja Wilmes, Steven Wink, Bob van de Water, Annette Kopp-Schneider, Frederic Y. Bois, Paul Jennings
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
transcriptomics
Nrf2
AhR
ATF4
toxicity pathways
toxicogenomic
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00429/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00429/full

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