The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response.

The C-type lectin receptor Mincle binds to Streptococcus pneumoniae but plays a limited role in the anti-pneumococcal innate immune response.

The innate immune system employs C-type lectin receptors (CLRs) to recognize carbohydrate structures on pathogens and self-antigens. The Macrophage-inducible C-type lectin (Mincle) is a FcRγ-coupled CLR that was shown to bind to mycobacterial cord factor as well as certain fungal species. However, s...

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Bibliographic Details
Main Authors: Anne Rabes, Stephanie Zimmermann, Katrin Reppe, Roland Lang, Peter H Seeberger, Norbert Suttorp, Martin Witzenrath, Bernd Lepenies, Bastian Opitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319728?pdf=render

Internet

http://europepmc.org/articles/PMC4319728?pdf=render

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