Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease.

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease.

Alzheimer disease (AD), Frontotemporal lobar degeneration (FTD), Amyotrophic lateral sclerosis (ALS) and Parkinson disease (PD) have a certain degree of clinical, pathological and molecular overlap. Previous studies indicate that causative mutations in AD and FTD/ALS genes can be found in clinical f...

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Main Authors: Maria Victoria Fernández, Jong Hun Kim, John P Budde, Kathleen Black, Alexandra Medvedeva, Ben Saef, Yuetiva Deming, Jorge Del-Aguila, Laura Ibañez, Umber Dube, Oscar Harari, Joanne Norton, Rachel Chasse, John C Morris, Alison Goate, NIA-LOAD family study group, NCRAD, Carlos Cruchaga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5683650?pdf=render

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