Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging.

Single-molecule super-resolution microscopy allows imaging of fluorescently-tagged proteins in live cells with a precision well below that of the diffraction limit. Here, we demonstrate 3D sectioning with single-molecule super-resolution microscopy by making use of the fitting information that is us...

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Bibliographic Details
Main Authors: Matthieu Palayret, Helen Armes, Srinjan Basu, Adam T Watson, Alex Herbert, David Lando, Thomas J Etheridge, Ulrike Endesfelder, Mike Heilemann, Ernest Laue, Antony M Carr, David Klenerman, Steven F Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4401716?pdf=render