Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes

Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes

The Na+/Ca2+ exchanger NCX3 is an important regulator of sodium and calcium homeostasis in oligodendrocyte lineage. To date, no information is available on the effects resulting from prolonged exposure to NCX3 blockers and subsequent drug washout in oligodendroglia. Here, we investigated, by means o...

Full description

Bibliographic Details
Main Authors: Mariarosaria Cammarota, Valeria de Rosa, Anna Pannaccione, Agnese Secondo, Valentina Tedeschi, Ilaria Piccialli, Ferdinando Fiorino, Beatrice Severino, Lucio Annunziato, Francesca Boscia
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
NCX3 exchanger
OPCs
Oligodendroglia
Myelin
BED blocker
Rebound effects
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008957

Internet

http://www.sciencedirect.com/science/article/pii/S0753332221008957

Similar Items