Toward the Pathogenicity of the<i> SLC26A4 </i>p.C565Y Variant Using a Genetically Driven Mouse Model

Toward the Pathogenicity of the<i> SLC26A4 </i>p.C565Y Variant Using a Genetically Driven Mouse Model

Recessive variants of the <em>SLC26A4</em> gene are globally a common cause of hearing impairment. In the past, cell lines and transgenic mice were widely used to investigate the pathogenicity associated with <em>SLC26A4</em> variants. However, discrepancies in pathogenicity...

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Bibliographic Details
Main Authors: Chin-Ju Hu, Ying-Chang Lu, Ting-Hua Yang, Yen-Hui Chan, Cheng-Yu Tsai, I-Shing Yu, Shu-Wha Lin, Tien-Chen Liu, Yen-Fu Cheng, Chen-Chi Wu, Chuan-Jen Hsu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>SLC26A4</i>
p.C565Y variant
Pendred syndrome
mice
human
Online Access:https://www.mdpi.com/1422-0067/22/6/2789

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https://www.mdpi.com/1422-0067/22/6/2789

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