Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

Aurora kinase A localises to mitochondria to control organelle dynamics and energy production

Many epithelial cancers show cell cycle dysfunction tightly correlated with the overexpression of the serine/threonine kinase Aurora A (AURKA). Its role in mitotic progression has been extensively characterised, and evidence for new AURKA functions emerges. Here, we reveal that AURKA is located and...

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Bibliographic Details
Main Authors: Giulia Bertolin, Anne-Laure Bulteau, Marie-Clotilde Alves-Guerra, Agnes Burel, Marie-Thérèse Lavault, Olivia Gavard, Stephanie Le Bras, Jean-Philippe Gagné, Guy G Poirier, Roland Le Borgne, Claude Prigent, Marc Tramier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
mitochondria
cell cycle
epithelial cancer
Online Access:https://elifesciences.org/articles/38111

Internet

https://elifesciences.org/articles/38111

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