A precision medicine classification for treatment of acute myeloid leukemia in older patients

A precision medicine classification for treatment of acute myeloid leukemia in older patients

Abstract Background Older patients (≥ 60 years) with acute myeloid leukemia (AML) often have multiple, sequentially acquired, somatic mutations that drive leukemogenesis and are associated with poor outcome. Beat AML is a Leukemia and Lymphoma Society-sponsored, multicenter umbrella study that algor...

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Bibliographic Details
Main Authors: Alice S. Mims, Jessica Kohlschmidt, Uma Borate, James S. Blachly, Shelley Orwick, Ann-Kathrin Eisfeld, Dimitrios Papaioannou, Deedra Nicolet, Krzysztof Mrόzek, Eytan Stein, Bhavana Bhatnagar, Richard M. Stone, Jonathan E. Kolitz, Eunice S. Wang, Bayard L. Powell, Amy Burd, Ross L. Levine, Brian J. Druker, Clara D. Bloomfield, John C. Byrd
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Hematology & Oncology
Subjects:
Acute myeloid leukemia
Mutation
Cytogenetics
Precision medicine
Outcome
Online Access:https://doi.org/10.1186/s13045-021-01110-5

Internet

https://doi.org/10.1186/s13045-021-01110-5

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