Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia—Relevance for Mental Diseases

Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia—Relevance for Mental Diseases

The heteroreceptor complexes present a novel biological principle for signal integration. These complexes and their allosteric receptor–receptor interactions are bidirectional and novel targets for treatment of CNS diseases including mental diseases. The existence of D2R-5-HT2AR heterocomplexes can...

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Bibliographic Details
Main Authors: Dasiel O. Borroto-Escuela, Patrizia Ambrogini, Manuel Narvaez, Valentina Di Liberto, Sarah Beggiato, Luca Ferraro, Ramon Fores-Pons, Jose E. Alvarez-Contino, Alexander Lopez-Salas, Giuseppa Mudò, Zaida Díaz-Cabiale, Kjell Fuxe
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
serotonin receptors
heteroreceptor complexes
depression
astroglia
receptor tyrosine kinase
rapid antidepressant drugs
Online Access:https://www.mdpi.com/2073-4409/10/8/1902

Internet

https://www.mdpi.com/2073-4409/10/8/1902

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