Deterministic Effects Propagation Networks for reconstructing protein signaling networks from multiple interventions

<p>Abstract</p> <p>Background</p> <p>Modern gene perturbation techniques, like RNA interference (RNAi), enable us to study effects of targeted interventions in cells efficiently. In combination with mRNA or protein expression data this allows to gain insights into the b...

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Bibliographic Details
Main Authors: Bender Christian, Arlt Dorit, Sahin Özgür, Fröhlich Holger, Beißbarth Tim
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/10/322