Hyaluronan promotes TRPV4-induced chondrogenesis in ATDC5 cells.

Hyaluronan (HA) is an extracellular matrix glycosaminoglycan essential for the homeostasis of cartilage-related tissues. Intracellular adhesion molecule-1 (ICAM-1) and CD44 have been identified as receptors for HA. Recently, transient receptor potential vanilloid 4 (TRPV4) has emerged as a potential...

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Bibliographic Details
Main Authors: Yoshikazu Ogawa, Nobunori Takahashi, Toki Takemoto, Tsuyoshi Nishiume, Mochihito Suzuki, Naoki Ishiguro, Toshihisa Kojima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219492