Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies

Abnormal deposition of misprocessed and aggregated proteins is a common final pathway of most neurodegenerative diseases, including Alzheimer’s disease (AD). AD is characterized by the extraneuronal deposition of the amyloid β (Aβ) protein in the form of plaques and the intraneuronal aggregation of...

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Bibliographic Details
Main Authors: Goran Šimić, Mirjana Babić Leko, Selina Wray, Charles Harrington, Ivana Delalle, Nataša Jovanov-Milošević, Danira Bažadona, Luc Buée, Rohan de Silva, Giuseppe Di Giovanni, Claude Wischik, Patrick R. Hof
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Biomolecules
Subjects:
Alzheimer’s disease
amyloid β
neurofibrillary degeneration
microtubules
neuropathology
phosphorylation
protein aggregation
protein oligomerization
tauopathies
tau protein
Online Access:http://www.mdpi.com/2218-273X/6/1/6

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http://www.mdpi.com/2218-273X/6/1/6

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