Targeting Tissue Factor to Tumor Vasculature to Induce Tumor Infarction

Targeting Tissue Factor to Tumor Vasculature to Induce Tumor Infarction

Besides its central functional role in coagulation, TF has been described as being operational in the development of malignancies and is currently being studied as a possible therapeutic tool against cancer. One of the avenues being explored is retargeting TF or its truncated extracellular part (tTF...

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Bibliographic Details
Main Authors: Andrew F. Berdel, Christian Schwöppe, Caroline Brand, Saliha Harrach, Kathrin Brömmel, Heike Hintelmann, Georg Lenz, Ruediger Liersch, Hauke Heinzow, Christoph Schliemann, Rolf M. Mesters, Wolfgang E. Berdel, Torsten Kessler
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
vascular targeting
tissue factor (TF)
truncated and retargeted tissue factor tTF-NGR
CD13
aminopeptidase N
tumor vascular occlusion
Online Access:https://www.mdpi.com/2072-6694/13/11/2841

Internet

https://www.mdpi.com/2072-6694/13/11/2841

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