Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult.

For more than thirty years, scutellarin (Scu) has been used in China to clinically treat acute cerebral infarction and paralysis. Scutellarein (Scue), the major Scu metabolite in vivo, exhibits heightened neuroprotective effects when compared to Scu. To explore the neuroprotective role of these comp...

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Bibliographic Details
Main Authors: Hao Tang, Yuping Tang, Nian-Guang Li, Hang Lin, Weixia Li, Qianping Shi, Wei Zhang, Pengxuan Zhang, Zexi Dong, Minzhe Shen, Ting Gu, Jin-Ao Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4493097?pdf=render