Bayesian adaptive designs for multi-arm trials: an orthopaedic case study

Abstract Background Bayesian adaptive designs can be more efficient than traditional methods for multi-arm randomised controlled trials. The aim of this work was to demonstrate how Bayesian adaptive designs can be constructed for multi-arm phase III clinical trials and assess potential benefits that...

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Bibliographic Details
Main Authors: Elizabeth G. Ryan, Sarah E. Lamb, Esther Williamson, Simon Gates
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-019-4021-0