Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread

Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread

Summary: Colorectal cancer (CRC) progression is a complex process that is not well understood. We describe an in vitro organ-on-chip model that emulates in vivo tissue structure and the tumor microenvironment (TME) to better understand intravasation, an early step in metastasis. The CRC-on-chip inco...

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Bibliographic Details
Main Authors: Carly Strelez, Sujatha Chilakala, Kimya Ghaffarian, Roy Lau, Erin Spiller, Nolan Ung, Danielle Hixon, Ah Young Yoon, Ren X. Sun, Heinz-Josef Lenz, Jonathan E. Katz, Shannon M. Mumenthaler
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Classification Description
Bioengineering
Tissue engineering
Cancer
Biomedical materials
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004776

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http://www.sciencedirect.com/science/article/pii/S2589004221004776

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