An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism.

Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D virus (IDV) was isolated from pigs and cattle. Here, we reveal that the IDV utilizes 9-O-acetylated sialic acids as its receptor for virus entry....

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Bibliographic Details
Main Authors: Hao Song, Jianxun Qi, Zahra Khedri, Sandra Diaz, Hai Yu, Xi Chen, Ajit Varki, Yi Shi, George F Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4729479?pdf=render