Next-generation sequencing of HIV-1 RNA genomes: determination of error rates and minimizing artificial recombination.

Next-generation sequencing of HIV-1 RNA genomes: determination of error rates and minimizing artificial recombination.

Next-generation sequencing (NGS) is a valuable tool for the detection and quantification of HIV-1 variants in vivo. However, these technologies require detailed characterization and control of artificially induced errors to be applicable for accurate haplotype reconstruction. To investigate the occu...

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Bibliographic Details
Main Authors: Francesca Di Giallonardo, Osvaldo Zagordi, Yannick Duport, Christine Leemann, Beda Joos, Marzanna Künzli-Gontarczyk, Rémy Bruggmann, Niko Beerenwinkel, Huldrych F Günthard, Karin J Metzner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24058534/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24058534/pdf/?tool=EBI

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