Human Granzyme B Based Targeted Cytolytic Fusion Proteins

Cancer immunotherapy aims to selectively target and kill tumor cells whilst limiting the damage to healthy tissues. Controlled delivery of plant, bacterial and human toxins or enzymes has been shown to promote the induction of apoptosis in cancerous cells. The 4th generation of targeted effectors ar...

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Bibliographic Details
Main Authors: Precious Hlongwane, Neelakshi Mungra, Suresh Madheswaran, Olusiji A. Akinrinmade, Shivan Chetty, Stefan Barth
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/6/2/72