Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets.

Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets.

Gene expression governs cell fate, and is regulated via a complex interplay of transcription factors and molecules that change chromatin structure. Advances in sequencing-based assays have enabled investigation of these processes genome-wide, leading to large datasets that combine information on the...

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Bibliographic Details
Main Authors: M S Vijayabaskar, Debbie K Goode, Nadine Obier, Monika Lichtinger, Amber M L Emmett, Fatin N Zainul Abidin, Nisar Shar, Rebecca Hannah, Salam A Assi, Michael Lie-A-Ling, Berthold Gottgens, Georges Lacaud, Valerie Kouskoff, Constanze Bonifer, David R Westhead
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007337

Internet

https://doi.org/10.1371/journal.pcbi.1007337

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