Meta‐analysis of genome‐wide DNA methylation and integrative omics of age in human skeletal muscle

Meta‐analysis of genome‐wide DNA methylation and integrative omics of age in human skeletal muscle

Abstract Background Knowledge of age‐related DNA methylation changes in skeletal muscle is limited, yet this tissue is severely affected by ageing in humans. Methods We conducted a large‐scale epigenome‐wide association study meta‐analysis of age in human skeletal muscle from 10 studies (total n = 9...

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Bibliographic Details
Main Authors: Sarah Voisin, Macsue Jacques, Shanie Landen, Nicholas R. Harvey, Larisa M. Haupt, Lyn R. Griffiths, Sofiya Gancheva, Meriem Ouni, Markus Jähnert, Kevin J. Ashton, Vernon G. Coffey, Jamie‐Lee M. Thompson, Thomas M. Doering, Anne Gabory, Claudine Junien, Robert Caiazzo, Hélène Verkindt, Violetta Raverdy, François Pattou, Philippe Froguel, Jeffrey M. Craig, Sara Blocquiaux, Martine Thomis, Adam P. Sharples, Annette Schürmann, Michael Roden, Steve Horvath, Nir Eynon
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Skeletal muscle
Ageing
Epigenetics
DNA methylation
Epigenetic clock
Meta‐analysis
Online Access:https://doi.org/10.1002/jcsm.12741

Internet

https://doi.org/10.1002/jcsm.12741

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